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Emerging approaches for the treatment of hypertriglyceridemia.

2013

Hypertriglyceridemia is frequent in diabetic and obese subjects, who are at increased risk for cardiovascular diseases (CVD). Increased triglycerides (TG) are a hallmark of atherogenic dyslipidemia, representing a marker of atherogenic small dense low-density lipoproteins (sdlDL). Importantly, non-fasting/postprandial TG measurements tend to be emphasized in clinical practice for the prediction of CVD, and TG-lowering agents (primarily fibrates) have a beneficial effect on atherogenic dyslipidemia, reducing TG-rich particles and ultimately lowering the production of sdlDL. The combination of omega-3 fatty acids and statins is also recommended, and widely used in clinical practice for subjec…

PharmacologyHypertriglyceridemiamedicine.medical_specialtyAtherogenic dyslipidemiabusiness.industryHypertriglyceridemiaGeneral Medicinemedicine.diseaseBioinformaticsFish consumptionClinical PracticeEndocrinologyIncreased riskPostprandialInternal medicinecardiovascular diseases triglycerides hypertriglyceridemia triglyceride-lowering agentsmedicineIncreased triglyceridesHumansPharmacology (medical)Obese subjectsbusinessLife StyleHypolipidemic AgentsExpert opinion on pharmacotherapy
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